For the first week the program includes lectures, poster sessions and informal discussions.
All of which takes place at the Hotel du Signal de Chexbres.
During the second and third week students perform two short research projects in laboratories of their choice.
Week 1
Sunday September 9th 2007
Monday September 10th - Imaging the motor system
Tuesday September 11th - Imaging synapses and neural activity in normal and diseased states
Wednesday September 12th - Imaging higher brain functions
Thursday September 13th - Reward processing in the brain
Friday September 14th - Autism / General discussion
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Weeks 2 & 3
Students will perform two experimental projects, one each week, choosing from a total of 26 projects (PDF
) offered by the following 23 laboratories:
| Number | Name | Institution | Project Title | Techniques / Notes | Related Articles | |
|---|---|---|---|---|---|---|
| 1 | Patrick Aebischer Jean-Charles Bensadoun Bernard Schneider Delphine Charvin |
BMI, EPFL, Lausanne | Therapeutic effects of polyphenols in Amyotrophic Lateral Sclerosis : from behavioural tests to motoneuron analyses. | - behavioural tests - electromyography - spinal cord slices preparation - staining and imaging of neuromuscular junctions and spinal motoneurons |
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| 2 | Paola Bezzi Jean-Yves Chatton Graham Knott |
DBCM/CIF/CEM, University of Lausanne | Imaging synaptic vesicles: structural and functional analysis | - Electron microscopy (preparation and imaging) - Total internal reflection fluorescence (TIRF) microscopy - Confocal microscopy - Photoconversion - Styryl dyes (FM1-43 or 4-64) - Immunocytochemistry - Image processing - 3D image reconstruction. |
Steyer & Almers 2001 Zenizek et al. 2000 Darcy et al. 2006 |
|
| 3 | Olaf Blanke | BMI, EPFL, Lausanne | Studying functional and neural interactions between corporeal awareness and self processing using high density electrical neuroimaging. | High-Density EEG | Blanke et al. 2005 Blanke & Mohr 2005 Arzy et al. 2006 |
|
| 4a | Rolf Gruetter Nathalie Just |
STI, EPFL, Lausanne | Vessel size index MR imaging at 9.4T | Troprčs et al. 2001 | ||
| 4b | Rolf Gruetter Gunnar Krueger |
CH F1 626, EPFL, Lausanne | "Resting state" fMRI | - fMRI - Image processing |
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| 4c | Rolf Gruetter Carole Poitry-Yamate |
IPMC/CIBM/LIFMET, EPFL, Lausanne | Quantitation of glucose and glycogen in rat brain: are there regional differences under varying glycemic conditions? |
- absorbance spectrophotometry - microdissection - neurochemistry techniques |
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| 4d | Rolf Gruetter Wietske van der Zwaag |
STI, EPFL, Lausanne | Physiological effects in high field MRI | fMRI | ||
| 5 | Nouchine Hadjikhani | BMI, EPFL, Lausanne | Visuo-social cognition in neurodevelopmental disorders | fMRI | ||
| 6 | Vicente Ibáńez Nathalie Ginovart Philippe Millet Marcelle Moulin-Sallanon |
HUG, Geneva | Dopaminergic neurotransmission: Changes in D2 receptors affinity and density under amphetamine challenge. | - PET - Phosphoimager - ex vivo binding |
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| 7 | Jozsef Kiss Alexandre Dayer |
CMU, Univesity of Geneva | Cellular dynamic of neural progenitor cells: analysis of cell migration and neurite outgrowth. | - time-lapse video analysis - imaging of transplanted cells in tissue - fluorescent and confocal optics - electron microscopy |
Zhang et al. 2003 Zhang et al. 2003 |
|
| 8 | Cécile Lebrand | DBCM, University of Lausanne | Transient GABAergic interneurons are required to guide commissural axons | - Organotypic slices - In vitro focal electroporation method - Confocal time-lapse video microscopy - Image processing |
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| 9 | Christian Lüscher | CMU, Univesity of Geneva | Characterization of the morphology of dopamine neurons in the VTA. | Two-Photon confocal line scanning microscope (Olympus Fluoview). | Cruz & Lüscher 2005 | |
| 10 | Fulvio Magara | University of Lausanne | ||||
| 11 | Pierre Marquet Pierre Magistretti |
BMI, EPFL, Lausanne | Study of the neuron-glial dynamics with digital holography microscopy. | - Digital holographic microscopy (DHM) - Video fluorescence microscopy and electrophysiology |
Rappaz et al. 2005 Marquet et al. 2005 |
|
| 12 | Christoph Michel Gregor Thut |
CMU/HUG, Univesity of Geneva | Mapping of brain electric activity by high density scalp and intracranial EEG in man and mice. | - High-Resolution (256-channel) scalp EEG and ERP in man - Multichannel epicranial EEG and EP in mice - Transcranial magnetic stimulation combined with EEG in man - Intracranial mutlichannel EEG in epileptic patients |
Michel et al. 2004 Michel et al. 2001 |
|
| 13 | Dominique Muller | CMU, Univesity of Geneva | Confocal imaging of synaptic plasticity and turn-over. | Slice cultures preparation, biolistic transfection, extracellular recordings, single photon and two-photon imaging of spines, time-lapse imaging. | ||
| 14 | Micah Murray | CHUV, Lausanne | Multisensory Interactions and Parallel Pathways in Human Sensory-Cognitive Processing. | 160 Channel EEG, electrical neuroimaging and psychophysics. | De Santis et al. 2006 Murray et al. 2004 Ghazanfar & Schroeder 2006 Murray et al. 2006 |
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| 15 | Carl Petersen | BMI, EPFL, Lausanne | Two-photon imaging in-vivo | In vivo two-photon imaging in anesthetised mice |
Petersen et al. 2003 Margrie et al. 2003 Tachtenberg et al. 2002 |
|
| 16 | Carmen Sandi Cristina Marquez Maria Toledo-Rodriguez |
LGC, BMI, EPFL, Lausanne | Imaging brain metabolism in an animal model of psychopathology | - Measuring 14C-2Deoxy-glucose signal in anatomically identified brain regions using the MCID system - Analyses of behavioural variable |
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| 17 | Françoise Schenk | Lausanne | ||||
| 18 | Ralf Schneggenburger | BMI, EPFL, Lausanne | ||||
| 19 | Armin Schnider Stephanie Morand |
HUG, Geneva | Reorganisation of cognitive functions after brain damage studied with high resolution electrical neuroimaging | - High-resolution scalp EEG in healthy subjects and patients - Behavioural tests | ||
| 20 | Sophie Schwartz | CMU, Univesity of Geneva | Neural plasticity and reactivation of memory traces during sleep as assessed by functional MRI and EEG in humans. | Intracranial EEG recordings (in patients), long-term scalp EEG recordings (in normal controls) and fMRI. | Stickgold 2005 Peigneux et al. 2004 Huber et al. 2004 Maquet et al. 2000 |
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| 21 | Dimitri van de Ville | BIG, EPFL, Lausanne | Statistical analysis and classification of fMRI brain data. | - MRI acquisition (anatomical and functional) - Signal & image processing - Statistical analysis - Classification techniques |
Van De Ville et al. 2006 | |
| 22 | Andrea Volterra Sabino Vesce |
DBCM, University of Lausanne | Two-photon in vivo imaging of glial cells | In vivo two-photon imaging in anesthetized mice | ||
| 23 | Patrik Vuilleumier | CMU, Univesity of Geneva | Functional neuroimaging of cognitive and emotional processing (fMRI & EEG) | fMRI, EEG and behavioural tests. |
Vuilleumier et al. 2004 Vuilleumier et al. 2001 Peelen et al. 2006 Sander et al. 2006 Sander et al. 2006 |